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October 30, 2026 — FxNutrition Intelligence
Evidence-driven intelligence for functional nutrition practitioners
A Nutrishify publication • Week of October 30, 2026
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SlimSEB, a probiotic, enzyme, and botanical blend, was tied to 4.51 kg lower adjusted weight than placebo in adults with obesity. Over two weeks, IBS symptom severity improved on a low-FODMAP diet, adapted NICE advice, and that advice plus intermittent fasting. Plus: coffee was linked to lower gout odds, and alcohol and sugary drinks were linked to higher odds.
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Evidence Spotlight
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Three Diets and IBS Symptoms
A two-week dietary comparison in 81 adults with irritable bowel syndrome (IBS) found symptom scores fell on a low-FODMAP diet, on adapted advice from NICE (National Institute for Health and Care Excellence), and on that advice plus intermittent fasting. The larger unadjusted drop with low-FODMAP versus NICE advice did not remain once the analysis accounted for how severe symptoms were at the start.
Quality of life improved in all three groups, and that between-group gap also disappeared after the same adjustment. Stool form did not differ between groups at the end. Anxiety scores fell only in the NICE arm. Assignment was not randomized, and follow-up lasted two weeks.
Takeaway: Symptom severity improved on a low-FODMAP diet, adapted NICE advice, and that advice plus intermittent fasting. No diet separated from the others once starting severity was included.
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Drinks, Uric Acid, and Gout
A meta-analysis of 52 observational studies tied alcohol and sugar-sweetened beverages (SSBs) to higher odds of gout and hyperuricemia. Alcohol odds were 1.809 for gout and 1.524 for high uric acid. SSB odds were 1.371 for gout and 1.478 for hyperuricemia. Coffee was associated with lower gout odds (0.543).
At usual intakes, tea was associated with higher hyperuricemia odds in women (1.294). Dose-response analyses pointed the same way for coffee, alcohol, and SSBs. The pooled studies were cross-sectional, cohort, and case-control work, not feeding trials.
Takeaway: Coffee was the beverage linked to lower gout odds. Alcohol and sugary drinks were linked to higher odds of gout and high uric acid. The analysis cannot show that changing a drink changes risk.
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Probiotic-Enzyme Blend and Weight
An 84-day randomized trial compared SlimSEB with a maltodextrin placebo in 87 adults with overweight or obesity and impaired fasting glucose (110–125 mg/dL). Diabetes was an exclusion. Adjusted weight was 2.60 kg lower than placebo in the overweight group and 4.51 kg lower in the obese group. SlimSEB is a capsule blend: five probiotic strains, including Lactiplantibacillus plantarum, at 1.5 billion CFU, digestive enzymes including SucroSEB, and 95.5 mg combined of mulberry leaf, green tea, cinnamon, and chromium picolinate. The dose was two capsules twice a day, 15–20 minutes before meals.
Adjusted hemoglobin A1c (HbA1c) was 0.65 and 0.67 percentage points lower than placebo. Waist size, fasting glucose, and insulin resistance also moved more with the blend. Eight mild adverse events were reported, none attributed to SlimSEB, and there were no serious events. The authors work at Advanced Enzymes, which is affiliated with Specialty Enzymes and Probiotics, the company that supplied the capsules. The trial tested the whole blend, so it does not show which ingredient produced the change. The supplier markets SlimSEB to brands formulating products, and the paper does not name a retail supplement at this dose.
Takeaway: The weight and HbA1c gaps apply to this whole blend, at two capsules twice a day, in adults with impaired fasting glucose and no diabetes diagnosis. The name is a supplier ingredient, not a finished product identified in the paper.
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By The Numbers
⬇︎4.51 kg
Adjusted weight was 4.51 kg lower with SlimSEB than placebo in adults with obesity.
That gap is the adjusted difference over 84 days in adults with obesity and impaired fasting glucose. SlimSEB is a probiotic, enzyme, and botanical blend from the supplier affiliated with the authors.
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Clinical Pearl
Three diets eased IBS symptoms
Over two weeks, IBS symptom severity improved on all three diets: low-FODMAP, adapted NICE (National Institute for Health and Care Excellence) advice, and that advice plus intermittent fasting. Quality of life improved in each arm as well. Once starting severity was included, no diet separated from the others.
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Recent Podcasts
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Depression, Nutrition, and Antidepressant Withdrawal: A Whole-Person Perspective
The Root Cause Medicine Podcast • October 29, 2026
Useful if clients ask about nutrition during depression care or antidepressant withdrawal. Dr. Kate Kresge talks with psychiatrist James Greenblatt, MD, about nutrition, laboratory assessment, and coming off antidepressants. Listen →
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Detox On A Budget, Migraine Root Causes & Solving GLP-1 Risks | Ask Me Anything
The Art of Being Well • October 29, 2026
Worth your time if clients are asking about glucagon-like peptide-1 (GLP-1) drugs, migraines, or a lower-cost detox plan. Will Cole answers listener questions on those three themes. Listen →
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From Acne to Anti-Aging: How Birth Control, Hormones & Gut Health Are Linked
DUTCH Podcast • October 27, 2026
A good listen when hormonal acne and skin aging come up together. Nigma Talib, NMD, and Dr. Jaclyn Smeaton connect gut dysbiosis, stress, hormone metabolism, and synthetic progestins with skin changes. Listen →
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The Science of BioActive Carbon with Dr. Todd Watts | THT Podcast Ep. 14
The Healing Terrain Podcast • October 27, 2026
Dr. Todd Watts discusses BioActive Carbon and why detoxification depends on energy, enzymes, and elimination pathways. The episode is product science from CellCore. Listen →
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An Anti-Wellness Approach to Clinical Nutrition
CNS Unfiltered • October 26, 2026
Useful when clients are buying wellness-branded food that is not actually nourishing. Jena Salisbury talks with Jessica Khourie, founder of Jova, about an anti-wellness approach: real food, products developed with scientists, and convenience that still has to deliver nutrition. Listen →
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Mark Your Calendar
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November 6
Navigating Cellular Health: BodyBio’s Interactive Q&A for Healthcare Professionals and Affiliates
Webinar | BodyBio | 11 AM–12 PM CT | Register →
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November 11
Feeding the Algorithm: Social Media for Nutrition Professionals in the Age of AI
Webinar | American Nutrition Association | 5 PM ET | CEUs available | Register →
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November 14
Food as Medicine for All Conference
Online | Food as Medicine Global | November 14–15 | $150 | CEUs available | Register →
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Org/Industry Updates
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Sprouted Buckwheat Powder
Big Bold Health is selling HTB Activ, a single-ingredient sprouted Himalayan Tartary Buckwheat powder with a toasted nutty flavor, ready to eat. The product page cites a 12-week randomized trial (Radicle Science 2026, n=662). Read more →
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Tech Tip
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AI scribes: what’s free and what isn’t
An AI scribe listens to a session and drafts the note. Several fit a nutrition practice:
| Tool |
Cost |
Good to know |
| Heidi (Heidi Health) |
Free tier; paid plans available |
Unlimited standard notes; 10 advanced actions a month on free |
| OpenEvidence Visits |
Free |
Verified U.S. healthcare professionals only; built for physicians |
| Practice Better AI Charting Assistant |
Add-on from $10/mo |
Works with any paid plan |
| Healthie AI Scribe |
$35/mo add-on (Plus plan and up) |
40 hours a month, shared across the account |
| Jane AI Scribe |
Add-on $15/mo per practitioner |
Every plan includes 5 free notes |
| Granola |
Free |
General meeting notes; HIPAA only on Enterprise |
Do this: get client consent before recording. If HIPAA applies to your practice, confirm the plan includes a signed BAA.
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